Injection site scores were normal in 50.3%, 73.2%, and 96.4% at 2 or 3, 11, and 54±3 days after the second injection, respectively. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
Figure 2. Additional increases in thickness were observed through Day 14 after injection. Repeated or prolonged exposure may lead to sensitization. var dfp728Slots = ; total Residues Of Ceftiofur Were Measured In The Lungs Of Cattle Administered Radiolabeled Ceftiofur At 1.0 Mg Ceftiofur Equivalents/lb (2.2 Mg/kg) Bw At 24 H Intervals For Five Consecutive Days. Subscribe to Drugs.com newsletters for the latest medication news, alerts, new drug approvals and more. ** Minimum inhibitory concentration (MIC) for 90% of the isolates. The cure rate was significantly higher (p < 0.0001) in EXCEDE-treated cows (362/493, 74.3%) than in vehicle-treated cows (271/489, 55.3%). We cannot confirm the completeness, accuracy and currency of the content. Selection of dosage level (0.5 to 1.0 mg/lb) and regimen/duration (daily or every other day for BRD only) should be based on an assessment of the severity of disease, pathogen susceptibility and clinical response. Ceftiofur crystalline free acid is a broad spectrum cephalosporin antibiotic active against gram-positive and gram-negative bacteria including β-lactamase-producing strains.
The initial increase in thickness is attributed to the space required for the volume of injected material. When clinical signs of acute post-partum metritis (rectal temperature ≥ 103°F and fetid vaginal discharge) were observed, 361 lactating dairy cows were assigned randomly to treatment or negative control. EXCEDE was superior to the saline control. A single injection of an antibiotic like Convenia is capable of working in your cat’s body for up to 14 days. Rectal temperatures 24 h after third treatment were 104.0°F, 103.1°F and 102.8°F for negative controls, 0.5 mg/lb and 1.0 mg/lb (1.1 or 2.2 mg/kg) BW, respectively. Save my name, email, and website in this browser for the next time I comment. A field dose confirmation study for the treatment of BRD evaluated the efficacy of single doses of 4.4 to 6.6 mg CE/kg BW for the treatment of the bacterial component of BRD under field conditions.
Table 2. INDICATIONS: EXCEDE Sterile Suspension is indicated for the treatment of Bovine Respiratory Disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni (formerly Haemophilus somnus) in beef and non-lactating dairy cattle. The comparability of plasma concentrations of ceftiofur following administration of ceftiofur hydrochloride sterile suspension (EXCENEL RTU Sterile Suspension) or ceftiofur sodium sterile solution (NAXCEL Sterile Powder) was demonstrated after intramuscular or subcutaneous administration of ceftiofur hydrochloride and intramuscular administration of ceftiofur sodium at 1.0 mg ceftiofur equivalents/lb (2.2 mg/kg) BW.
The ventral base of the ear injection technique was evaluated in a conditions of use study in 200 beef cattle. There was a statistically significant difference (p = 0.0054) in treatment success for EXCEDE-treated cattle (58.4%) compared to vehicle-treated control cattle (13.2%).
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